Precision Variable


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BK PRECISION 1655 VARIABLE AC POWER SUPPLY


BK PRECISION 1655 VARIABLE AC POWER SUPPLY


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BK Precision Power Supply 1653A, Variable Output, Analog


BK Precision Power Supply 1653A, Variable Output, Analog


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BK PRECISION VARIABLE AC POWER SUPPLY MODEL 1655


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Waveline 1022-R Variable Precision Rotary Vane Attenuators WR28 40GHz


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Weinschel Eng. Precision Variable Attenuator, Model#64


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1000pcs,3296 101 100ohm Variable Resistor Precision NEW


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1000pcs, 3296 504 500K Variable Resistor Precision


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1000pcs, 3296 105 1M Variable Resistor Precision


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1000pcs, 3296 202 2K Variable Resistor Precision


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1000pcs, 3296 103 10K Variable Resistor Precision


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PRECISION VARIABLE/ DECADE RESISTOR/RESIS​TANCE BOX


PRECISION VARIABLE/ DECADE RESISTOR/RESIS​TANCE BOX


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1000pcs, 3296 102 1K Variable Resistor Precision


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1000pcs, 3296 502 5K Variable Resistor Precision


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PRECISION VARIABLE ADJUSTABLE 30V 3A DC POWER SUPPLY For Mobile, Service Repair


PRECISION VARIABLE ADJUSTABLE 30V 3A DC POWER SUPPLY For Mobile, Service Repair


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High Precision Variable 30V 5A DC Power Supply Lab Grad


High Precision Variable 30V 5A DC Power Supply Lab Grad


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High Precision Variable 30V 5A DC Power Supply Lab Grad


High Precision Variable 30V 5A DC Power Supply Lab Grad


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YH-305D Digital DC Power Supply Precision Variable Adjustable Lab Grade 30V 5A


YH-305D Digital DC Power Supply Precision Variable Adjustable Lab Grade 30V 5A


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High Precision Variable 30V 5A DC Power Supply Lab Grad


High Precision Variable 30V 5A DC Power Supply Lab Grad


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PRECISION VARIABLE/ DECADE CAPCITOR BOX model 501


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USA Brand Precision Lab GQ-A305D Variable 30V 5A DC Power Supply w/ CV & CC mode


USA Brand Precision Lab GQ-A305D Variable 30V 5A DC Power Supply w/ CV & CC mode


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VINTAGE General Radio 722-N 722 Precision Variable capacitor condenser (tag# 30)


VINTAGE General Radio 722-N 722 Precision Variable capacitor condenser (tag# 30)


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Precision Lab PS305D Variable 30V 5A DC Power Supply


Precision Lab PS305D Variable 30V 5A DC Power Supply


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Digital DC Power Supply 30V 5A Precision Variable Adjustable Lab Grade X5045


Digital DC Power Supply 30V 5A Precision Variable Adjustable Lab Grade X5045


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Weinschel 940-114-33 Precision Continuously Variable Attenuator  4GHz , 114dB


Weinschel 940-114-33 Precision Continuously Variable Attenuator 4GHz , 114dB


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Precision Lab GQ-A305D Variable 30V 5A DC Power Supply with CC & CV mode 0~30V


Precision Lab GQ-A305D Variable 30V 5A DC Power Supply with CC & CV mode 0~30V


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0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


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High Precision 3266W Variable Resistors 5K Ohm 350pcs


High Precision 3266W Variable Resistors 5K Ohm 350pcs


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High Precision 3266W Variable Resistors 10K Ohm 350pcs


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High Precision 3266W Variable Resistors 2K Ohm 350pcs


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High Precision 3266W Variable Resistors 200K Ohm 350pcs


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High Precision 3266W Variable Resistors 50K Ohm 350pcs


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High Precision 3266W Variable Resistors 100K Ohm 350pcs


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High Precision 3266W Variable Resistors 1K Ohm 350pcs


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High Precision 3266W Variable Resistors 500K Ohm 350pcs


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Precision Lab GQ-A305D Variable 30V 5A DC Power Supply with CC & CV mode 0~30V


Precision Lab GQ-A305D Variable 30V 5A DC Power Supply with CC & CV mode 0~30V


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0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


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LOT OF 2 Laser Precision DB-2900  Singlemode Variable  OPTICAL ATTENUATOR


LOT OF 2 Laser Precision DB-2900 Singlemode Variable OPTICAL ATTENUATOR


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0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


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0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


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Precision Variable 0-30V 5A DC Power Supply USA Product


Precision Variable 0-30V 5A DC Power Supply USA Product


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Precision Lab PS305D Variable 30V 5A DC Power Supply


Precision Lab PS305D Variable 30V 5A DC Power Supply


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GQ-A305D Precision Lab Variable 0~30V 5A DC Power Supply with C.C. and C.V. mode


GQ-A305D Precision Lab Variable 0~30V 5A DC Power Supply with C.C. and C.V. mode


$94.00


Precision Variable Decade Resistor Resistance Box ZX21


Precision Variable Decade Resistor Resistance Box ZX21


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Precision Variable decade resistor resistance Box ZX21


Precision Variable decade resistor resistance Box ZX21


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Precision Variable decade resistor resistance Box ZX21


Precision Variable decade resistor resistance Box ZX21


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Precision Variable decade resistor resistance Box ZX21


Precision Variable decade resistor resistance Box ZX21


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0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


0~99999.9 6 knob PRECISION VARIABLE DECADE RESISTOR BOX


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30V 3A Digital DC Power Supply Precision Variable Adjustable Lab Grade New


30V 3A Digital DC Power Supply Precision Variable Adjustable Lab Grade New


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NEW Precision Variable Decade Resistor Resistance Box


NEW Precision Variable Decade Resistor Resistance Box


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NEW PRECISION VARIABLE/ DECADE RESISTOR/RESISTANCE BOX


NEW PRECISION VARIABLE/ DECADE RESISTOR/RESISTANCE BOX


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Precision Variable decade DC resistor resistance Box


Precision Variable decade DC resistor resistance Box


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30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


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30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


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30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


30V 5A Precision Variable DC Power Supply Clip Cable Digital Adjustable Lab Grad


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X5045 Pro 30V 5A Digital DC Power Supply Precision Variable Adjustable


X5045 Pro 30V 5A Digital DC Power Supply Precision Variable Adjustable


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Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


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Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


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Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


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Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


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Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


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Digital DC Power Supply 30V 5A Precision Variable Adjustable Lab Grade


Digital DC Power Supply 30V 5A Precision Variable Adjustable Lab Grade


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Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


Precision Variable Adjustable 30V 5A DC Power Supply Digital Regulated Lab Grade


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30V 5A Digital DC Power Supply Precision Variable Adjustable Lab Grade PS305 New


30V 5A Digital DC Power Supply Precision Variable Adjustable Lab Grade PS305 New


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30V 5A 110V Precision Variable DC Power Supply w Clip Cable Digital Adjustable


30V 5A 110V Precision Variable DC Power Supply w Clip Cable Digital Adjustable


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Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


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Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


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Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


Precision Adjustable Variable 30V 2A DC Power Supply Lab Regulated Grade


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High Precision 3362 Variable Resistors 5K Ohm 350pcs


High Precision 3362 Variable Resistors 5K Ohm 350pcs


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High Precision 3362 Variable Resistors 10K Ohm 350pcs


High Precision 3362 Variable Resistors 10K Ohm 350pcs


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High Precision 3296 Variable Resistors 5K Ohm 350pcs


High Precision 3296 Variable Resistors 5K Ohm 350pcs


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High Precision 3362 Variable Resistors 20K Ohm 350pcs


High Precision 3362 Variable Resistors 20K Ohm 350pcs


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High Precision 3296 Variable Resistors 2K Ohm 350pcs


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High Precision 3296 Variable Resistors 1K Ohm 350pcs


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High Precision 3362 Variable Resistors 50K Ohm 350pcs


High Precision 3362 Variable Resistors 50K Ohm 350pcs


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High Precision 3296 Variable Resistors 20K Ohm 350pcs


High Precision 3296 Variable Resistors 20K Ohm 350pcs


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High Precision 3296 Variable Resistors 10K Ohm 350pcs


High Precision 3296 Variable Resistors 10K Ohm 350pcs


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High Precision 3362 Variable Resistors 2K Ohm 350pcs


High Precision 3362 Variable Resistors 2K Ohm 350pcs


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High Precision 3296 Variable Resistors 50K Ohm 350pcs


High Precision 3296 Variable Resistors 50K Ohm 350pcs


$68.86


High Precision 3296 Variable Resistors 200K Ohm 350pcs


High Precision 3296 Variable Resistors 200K Ohm 350pcs


$68.86


High Precision 3296 Variable Resistors 100K Ohm 350pcs


High Precision 3296 Variable Resistors 100K Ohm 350pcs


$68.86


High Precision 3362 Variable Resistors 200K Ohm 350pcs


High Precision 3362 Variable Resistors 200K Ohm 350pcs


$68.86


High Precision 3362 Variable Resistors 1K Ohm 350pcs


High Precision 3362 Variable Resistors 1K Ohm 350pcs


$68.86


High Precision 3296 Variable Resistors 500K Ohm 350pcs


High Precision 3296 Variable Resistors 500K Ohm 350pcs


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High Precision 3362 Variable Resistors 500K Ohm 350pcs


High Precision 3362 Variable Resistors 500K Ohm 350pcs


$68.86


High Precision 3362 Variable Resistors 100K Ohm 350pcs


High Precision 3362 Variable Resistors 100K Ohm 350pcs


$68.86


Precision Variable 0-15V 2A DC Power Supply Cellphone


Precision Variable 0-15V 2A DC Power Supply Cellphone


$58.00


Precision Variable 0-15V 2A DC Power Supply Cellphone


Precision Variable 0-15V 2A DC Power Supply Cellphone


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Bourns Precision Potentiometers, 5 kΩ/5 W, Variable Resistors, 3400S-1-502, NEW


Bourns Precision Potentiometers, 5 kΩ/5 W, Variable Resistors, 3400S-1-502, NEW


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High Precision 3266W Variable Resistors 200K Ohm 150pcs


High Precision 3266W Variable Resistors 200K Ohm 150pcs


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Elenco Precision XP-581 Quad Power Regulated Power Supply 2-20v Variable


Elenco Precision XP-581 Quad Power Regulated Power Supply 2-20v Variable


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High Precision 3266W Variable Resistors 20K Ohm 150pcs


High Precision 3266W Variable Resistors 20K Ohm 150pcs


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Precision Variable Questions

Precision Variable

Variability in the measurement of Lipoprotein (a)

What is Lipoprotein (a)?

 

High levels of lipoprotein (a) are associated with an increased risk of developing coronary heart disease, cerebrovascular disease, atherosclerosis, thrombosis or stroke.  Lp(a) is of particular use in assessing the risk of cardiovascular disease in specific populations as it is genetically determined and is known to vary with ethnic populations.

 

Lp(a) is an LDL like particle with a molecule of Apolipoprotein B-100 linked by a disulphide bridge to Apolipoprotein (a).  The apo(a) component is similar to plasminogen in terms of structure and competes with plasminogen for binding sites resulting in reduced fibrinolysis and the formation of blood clots.  Lp(a) is also thought to speed up the process of atherosclerosis by binding LDL, calcium and other components into an atherosclerotic plaque on the blood vessel wall.   This dual action of Lp(a) explains its role in the promotion of cardiovascular disease.

 

Apolipoprotein (a) size related bias


The plasma concentration of Lp(a) varies greatly from person to person due to the apo(a) component.  Apo(a) is unique in that it is extremely heterogeneous in size; it is made up of a variable number of repeat structures known as kringles. The size heterogeneity of apo(a) is due to the kringle 4 domain and the kringle 4 type 2 domain in particular which can be present in a variable number of repeat copies ranging from 10 to more than 50.  These variable sizes are called apo(a) isoforms and account for the differences in Lp(a) concentration.

 

The use of Lp(a) as an independent risk factor for cardiovascular disease risk has been impeded by the lack of internationally accepted standardisation and the fact that many commercial Lp(a) methods suffer from apolipoprotein (a) size related bias.

 

The size heterogeneity of apo(a) affects to varying degrees the outcome of many commercially available Lp(a) kits as the antibodies employed react specifically with the repeat sequences giving different results depending on the number of repeats.

 

Where size related bias is observed, the more repeat sequences the more antibody binds resulting in a greater immunoturbidimetric signal and an overestimated result.  Similarly in samples containing a small apo(a) molecule the Lp(a) result will be underestimated.

 

With Randox there is no size related bias as the antibody detects the complete Lp(a) molecule providing consistent and correct results.

 

Why use the Randox <a href=” <a href=”http://www.randox.com/lipid profile.php”>http://www.randox.com/lipid profile.php”>Lipoprotein (a) kit</a>?

 

The Randox liquid ready to use Lp(a) kit provides a highly sensitive and specific method for the detection of Lp(a) in serum and plasma, furthermore it is one of the only methods to exhibit minimum apo(a) size related bias.

 

The antibody used in the Randox method detects the complete Lp(a) molecule providing accurate and consistent results.  Research has documented and shown the Randox method to be one of only few to exhibit minimum size related bias.  The International Federation of Clinical Chemistry (IFCC) have conducted studies which clearly highlight the extent of the problem in other commercially available products and now recommend laboratories use tests from suppliers who do not suffer from apo(a) size related bias.

 

Not only is the Randox Lp(a) kit robust against apo(a) size heterogeneity it is also standardised to the WHO/IFCC reference material SRM 2B and is closest in terms of agreement to the ELISA reference method.  Other benefits of the Randox Lp(a) kit include:

 

  • Liquid ready to use reagents
  • Excellent stability – open vial stability of 30 days on board the analyser at 10oC
  • Dynamic assay range 3 – 90 mg/dl
  • Excellent precision – within run CVs <3%
  • No sample preparation required
  • Limited interference from Intralipid®, Bilirubin, Haemoglobin, Ascorbic Acid, Triglycerides, Plasminogen and Apolipoprotein B
  • Antigen excess effects are not noted up to 341 mg/dl
  • Dedicated or multi-analyte controls and calibrators available
  • Fully automated applications available for a wide range of clinical analysers

 

 

About the Author

Headquartered in the United Kingdom, Randox Laboratories Ltd. is a market leader within the in vitro diagnostics industry, manufacturing high quality diagnostic products for laboratories worldwide. Our extensive product portfolio offers complete solutions within the fields of forensic toxicology, clinical chemistry, cardiology, veterinary, drug residues, life sciences, oncology, molecular diagnostics and internal and external quality control. A continuous strategy of innovation has allowed Randox to revolutionise technology for the forensic toxicology market. Significant re-investment in Research and Development has seen the novel Biochip Array Technology adapt and evolve, with four analysers available for various settings. Twenty international offices and over one hundred distribution partners, ensure a high level of customer service worldwide.

 

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